The
Waters 2414 Refractive Index Detector is well-suited to analyze compounds that are without strong UV chromophores, fluorophores, or electrochemical or ionic activity. RI detectors are used to analyze carbohydrates and lipids and in polymer analyses by gel-permeation or size-exclusion chromatography. RI detectors work by measuring changes in the bulk properties of the solvent and the solutes under investigation, exploiting the improbability that solvents and solutes would share the identical refractive index.
The
2414 refractive index detector uses monochromatic light at a fixed wavelength. The detector is also able to monitor temperature as an auxiliary channel.
The
2414 detector operates as a single-channel detector, but can be configured to operate in one of two modes to acquire refractive index signal data:
- RIU mode: this is the default mode, standalone operating mode
which monitors a single channel using micro-refractive index units (µRIUs).
- 410 emulation mode: This mode is automatically reconfigured and activated when the 2414 detector is operated by data control system. This also allows you to configure several additional parameters.
Waters
2414 Refractive Index (RI) Detector is designed for high-performance liquid chromatography (HPLC) applications. It provides sensitivity, stability, and reproducibility for the analysis of components with limited or no UV absorption. The solution-centered design combines with Alliance or Breeze HPLC Systems for RI-based HPLC and GPC applications.
Waters
2414 RI Detector provides solutions for preparative and analytical applications including alcohol, sugar, saccharide, fatty acid, and polymer analysis.
