LD Technology TM Flow Autonomic Nervous System Testing Machine

DESCRIPTION

The LD Technology TM-Flow System is a patented medical device designed for the early detection and monitoring of chronic disease complications, particularly related to cardiovascular risk factors such as hypertension, obesity, smoking, and diabetes. It is a non-invasive system that tests and monitors the autonomic nervous system and vascular function, providing valuable data for physicians to assess patients who may have suffered from complications of chronic diseases. The system comprises three devices (TBL-ABI, OXI W, SweatC) and a dedicated software, along with a cloud platform for data management. The TM-Flow System is aimed at enabling early detection, which is crucial for timely treatment of chronic disease complications. It is particularly relevant for populations over 50 years old with cardiovascular risk factors and those over 70 years old. The system's clinical applications are focused on the early detection of chronic disease complications, such as those related to diabetes.

ADDITIONAL INFORMATION

FEATURES:

• Autonomic Assessment: 
  • Sudomotor Function Markers
  • Heart rate variability Analysis (HRV).
     
• Cardiac Autonomic Reflex Tests:
  • Valsalva Ratio
  • E/I Ratio
  • K30/15 Ratio
  • Systolic and diastolic Pressure Response to Standing
     
• Lifestyle Assessment 
  • BMI and Fat mass percent 
  • Vital signs 
  • HRV markers of exercise capacity
     
• Vascular Assessment:
  • Arterial stiffness
  • Ankle Brachial Indices 
  • Volume plethysmography analysis
  • Endothelial Function
  • Patented markers from mathematical analysis of the photoplethysmography spectral analysis
     
• TM Flow Clinical Validation: 
  • PTG Spectral Analysis Markers returned a high correlation with:
    • The gold standard of Insulin resistance assessment.
    • Vascular blood tests (CRP and fibrinogen)
  • PTG Spectral Analysis Markers returned a high sensitivity and specificity to detect the  Coronary Heart Disease 
  • The Cardiometabolic Score returned a high correlation with the Oral Glucose Tolerance Test (OGTT)
  • Sudomotor markers returned a high sensitivity and specificity to detect:​
    • Small fiber Neuropathy Symptoms
    • Microvascular disease (retinopathy)