An ultrasonic homogenizer works by using a combination of force, high temperatures, and pressure caused through a process called acoustic cavitation. This causes small bubbles to form and grow, merge with one another, and finally collapse. This causes a shockwave that has enough energy to disrupt cells. Mechanical homogenizers are another option. They have several different styles readily available, including blade, rotor-stator, and bead mills. They use agitation of the samples and their grinding media, such as ceramic, to disrupt tissue of animals and plants, as well as microorganisms. The pressure homogenizers utilize pressure and the forces it creates as a means to disrupt the cells.