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Since there are so many different types and styles of homogenizers available today, the features actually vary quite a bit. There are handheld and bench top models available and the speeds within each can vary. The homogenizers will typically run between 5,000 and 30,000 RPM, but each model and style will be different. More features and options are being added to these devices all the time to make them even more useful to the scientific community.
How homogenizers work
An ultrasonic homogenizer works by using a combination of force, high temperatures, and pressure caused through a process called acoustic cavitation. This causes small bubbles to form and grow, merge with one another, and finally collapse. This causes a shockwave that has enough energy to disrupt cells. Mechanical homogenizers are another option. They have several different styles readily available, including blade, rotor-stator, and bead mills. They use agitation of the samples and their grinding media, such as ceramic, to disrupt tissue of animals and plants, as well as microorganisms. The pressure homogenizers utilize pressure and the forces it creates as a means to disrupt the cells.
Homogenizers can utilize one of several different methods to perform their tasks – pressure, ultrasonic, or mechanical means. Homogenization is a very important step when it comes to preparing samples when analyzing things such as pathogens, cells, protein, and nucleic acid. Since each of the methods of homogenization varies, it is important to understand a bit about each one before you can choose the best option for your rental.